Which of the following signs and symptoms are indicative of cystic fibrosis?

Cystic fibrosis is a genetic disorder that primarily affects the lungs and digestive system, characterized by the production of thick, sticky mucus. The signs and symptoms of cystic fibrosis are often related to respiratory issues and digestive complications.

Addressing the choice that is considered correct: steatorrhea, which is the presence of excess fat in the stools, indicates malabsorption due to pancreatic insufficiency often seen in cystic fibrosis. Meconium ileus, the obstruction of the intestine in newborns due to thick meconium, is notably a classic symptom that can signal the presence of cystic fibrosis at birth. Both of these signs illustrate the digestive complications frequently associated with the condition.

While other options also mention symptoms that can be related to cystic fibrosis, the presence of steatorrhea and meconium ileus specifically highlights the underlying issues that are characteristic of the disease and are frequently used for diagnosis. Frequent respiratory infections, salty sweat, and wheezing, while relevant, might not uniquely point to cystic fibrosis without the context of digestive symptoms. Therefore, the combination of steatorrhea and meconium ileus is a more definitive indicator of the disease.