Which finding may indicate cystic fibrosis in a newborn?

The presence of meconium ileus in a newborn is a significant finding that may indicate cystic fibrosis. Cystic fibrosis is a genetic disorder that affects the exocrine glands, leading to thick and sticky mucus production, which can cause blockages in various organs, particularly the intestines and lungs.

In newborns with cystic fibrosis, the meconium—the first feces passed after birth—can become thickened and can obstruct the intestine, resulting in meconium ileus. This condition is often one of the earliest signs of cystic fibrosis and is observed in about 10-20% of affected infants. Recognizing meconium ileus is crucial for early diagnosis and management of cystic fibrosis, as it can lead to serious complications if not treated promptly.

While steatorrhea, which refers to fatty stools, might be associated with cystic fibrosis due to pancreatic insufficiency later in life, it is not typically a finding seen in newborns. Similarly, auscultation of wheezing could indicate respiratory issues, but it is not specific to cystic fibrosis and can arise from a variety of other conditions. Excessive crying does not directly correlate with cystic fibrosis and is a nonspecific symptom that can result